Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28830732 | 0.81 | PSEN1 (0.44) | ALDH1A1TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28076445 | 0.81 | ALDH1A1 (0.40) | ALDH1A1RAB9ALMNAAAK1 | |
| SCHEMBL27770762 | 0.81 | MAPT (0.46) | CYP1A2L3MBTL1ADRB2ADRB1ADRB3 | |
| SCHEMBL28136985 | 0.77 | SLC6A2 (0.41) | CYP1A2MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL4705983 | 0.76 | ALDH1A1 (0.54) | ALDH1A1RAB9APOLBNR4A1HSD17B10 | |
| SCHEMBL28041868 | 0.76 | CA1 (0.45) | ALDH1A1RAB9APOLBNR4A1HSD17B10 | |
| SCHEMBL28094567 | 0.75 | DPP4 (0.39) | ALDH1A1POLBSLC6A2SLC6A3MAPT | |
| SCHEMBL18599484 | 0.75 | ALDH1A1 (0.49) | ALDH1A1RAB9APOLBNR4A1HSD17B10 | |
| SCHEMBL4598418 | 0.74 | MEN1 (0.48) | ALDH1A1RAB9APOLBNR4A1HSD17B10 | |
| SCHEMBL4598417 | 0.74 | MEN1 (0.48) | ALDH1A1RAB9APOLBNR4A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104981470-A | Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use | Bayer Pharma AG | 2015-10-14 | — | — | CN | disclosed |