SCHEMBL28041995

SCHEMBL28041995

Cc1c(N)ccc2c1[nH]c1ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.59
MAPK1 P28482 2/20 0.59
NPSR1 Q6W5P4 2/20 0.59
KIF11 P52732 6/20 0.56
ALDH1A1 P00352 3/20 0.50
HSD17B10 Q99714 3/20 0.50
GABRP O00591 2/20 0.50
GABRD O14764 2/20 0.50
GABRA1 P14867 2/20 0.50
GABRB1 P18505 2/20 0.50
GABRG2 P18507 2/20 0.50
GABRB3 P28472 2/20 0.50
GABRA5 P31644 2/20 0.50
GABRA3 P34903 2/20 0.50
GABRA2 P47869 2/20 0.50
GABRB2 P47870 2/20 0.50
GABRA4 P48169 2/20 0.50
GABRE P78334 2/20 0.50
GABRA6 Q16445 2/20 0.50
GABRG1 Q8N1C3 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL146378 0.81 KIF11 (0.66) MAPTMAPK1NPSR1KIF11ALDH1A1
SCHEMBL67665 0.81 KIF11 (0.55) MAPTMAPK1NPSR1KIF11ALDH1A1
SCHEMBL29726990 0.81 KIF11 (0.66) MAPTMAPK1NPSR1KIF11ALDH1A1
SCHEMBL16414204 0.80 MAPT (0.50) MAPTMAPK1NPSR1KIF11ALDH1A1
Hydrochloric Acid SCHEMBL572039 0.79 KIF11 (0.63) MAPTMAPK1NPSR1KIF11ALDH1A1
Ammonia Solution, Strong SCHEMBL28022012 0.79 KIF11 (0.63) MAPTMAPK1NPSR1KIF11ALDH1A1
SCHEMBL27439693 0.79 MAPT (0.54) MAPTMAPK1NPSR1KIF11ALDH1A1
SCHEMBL23166719 0.78 KIF11 (0.56) MAPTMAPK1NPSR1KIF11ALDH1A1
SCHEMBL3872869 0.78 KIF11 (0.52) MAPTMAPK1NPSR1KIF11ALDH1A1
SCHEMBL8802523 0.78 KIF11 (0.56) MAPTMAPK1NPSR1KIF11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117105950-A Fluorescent probe for myeloperoxidase detection and preparation method and application thereof 温州医科大学 2023-11-24 CN disclosed
CN-107011342-A The preparation based on carboline and carbazole for detecting neurological dysfunction 伊莱利利公司 2017-08-04 CN disclosed
CN-105136787-A Detection reagent for mono-hydroxyphenyl metabolin urine SHANGHAI FEI JI BIOTECHNOLOGY CO LTD 2015-12-09 CN disclosed