SCHEMBL28042218

SCHEMBL28042218

Cc1nc2ccccc2c(C)c1N

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.62
HSD17B10 Q99714 4/20 0.62
HPGD P15428 4/20 0.62
NUDT1 P36639 2/20 0.62
CYP1A2 P05177 2/20 0.62
GPR3 P46089 1/20 0.57
TP53 P04637 2/20 0.56
KDM4E B2RXH2 4/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
GLA P06280 2/20 0.56
CASP1 P29466 2/20 0.56
CASP7 P55210 2/20 0.56
ACHE P22303 2/20 0.56
CHRM2 P08172 1/20 0.56
ADRA2A P08913 1/20 0.56
ADORA3 P0DMS8 1/20 0.56
CHRM1 P11229 1/20 0.56
NQO2 P16083 1/20 0.56
MAOA P21397 1/20 0.56
DRD1 P21728 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27296318 0.89 ALDH1A1 (0.64) ALDH1A1HSD17B10HPGDNUDT1CYP1A2
SCHEMBL30025532 0.89 ALDH1A1 (0.64) ALDH1A1HSD17B10HPGDNUDT1CYP1A2
SCHEMBL440157 0.85 ALDH1A1 (0.64) ALDH1A1HSD17B10HPGDNUDT1CYP1A2
SCHEMBL231530 0.85 GPR3 (0.64) ALDH1A1HSD17B10HPGDNUDT1CYP1A2
Ammonia Solution, Strong SCHEMBL28822932 0.83 GPR3 (0.61) ALDH1A1HSD17B10HPGDNUDT1CYP1A2
Hydrochloric Acid SCHEMBL27521191 0.83 GPR3 (0.61) ALDH1A1HSD17B10HPGDNUDT1CYP1A2
SCHEMBL2719248 0.80 HSD17B10 (0.58) ALDH1A1HSD17B10HPGDNUDT1CYP1A2
SCHEMBL8061027 0.80 HSD17B10 (0.58) ALDH1A1HSD17B10HPGDNUDT1CYP1A2
SCHEMBL15978466 0.80 ALDH1A1 (0.52) ALDH1A1HSD17B10HPGDNUDT1CYP1A2
SCHEMBL28878310 0.80 ALDH1A1 (0.52) ALDH1A1HSD17B10HPGDNUDT1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105136787-A Detection reagent for mono-hydroxyphenyl metabolin urine SHANGHAI FEI JI BIOTECHNOLOGY CO LTD 2015-12-09 CN disclosed