Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | ACHE | P22303 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | NQO2 | P16083 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30583435 | 0.82 | ACHE (0.64) | ALDH1A1HSD17B10KDM4EHPGDACHE | |
| SCHEMBL27943843 | 0.82 | TDP1 (0.52) | ALDH1A1HSD17B10KDM4EHPGDACHE | |
| SCHEMBL210949 | 0.82 | ACHE (0.64) | ALDH1A1HSD17B10KDM4EHPGDACHE | |
| SCHEMBL5469806 | 0.80 | MAOA (0.56) | ALDH1A1HSD17B10KDM4EHPGDACHE | |
| SCHEMBL28042218 | 0.80 | ALDH1A1 (0.62) | ALDH1A1HSD17B10KDM4EHPGDACHE | |
| Hydrochloric Acid SCHEMBL843193 | 0.80 | RAB9A (0.65) | ALDH1A1HSD17B10KDM4EHPGDACHE | |
| SCHEMBL12874595 | 0.80 | MAOA (0.61) | ALDH1A1HSD17B10KDM4EHPGDACHE | |
| SCHEMBL30631523 | 0.77 | MAOA (0.47) | ALDH1A1HSD17B10KDM4EHPGDMAOA | |
| SCHEMBL28878310 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KDM4EHPGDACHE | |
| SCHEMBL27549449 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KDM4EHPGDACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3950687-A1 | INDUSTRIAL METHOD FOR SYNTHESISING IMIQUIMOD FROM QUINOLINE-2,4-DIOL APPLICABLE TO THE PHARMACEUTICAL USE THEREOF | PHV Pharma (FR) | 2022-02-09 | — | — | EP | disclosed |
| US-9873694-B2 | Imidazole quinoline-based immune system modulators | JANUS BIOTHERAPEUTICS, INC. (US) | 2018-01-23 | — | — | US | disclosed |
| US-20140242121-A1 | NOVEL IMIDAZOLE QUINOLINE-BASED IMMUNE SYSTEM MODULATORS | JANUS BIOTHERAPEUTICS, INC. (US) | 2014-08-28 | — | — | US | disclosed |
| CN-101370765-B | Method for selectively producing primary amine | SUMITOMO CHEMICAL CO | 2013-03-13 | — | — | CN | disclosed |
| CN-101370765-A | Method for selectively producing primary amine | SUMITOMO CHEMICAL CO (JP) | 2009-02-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140242121-A1 | NOVEL IMIDAZOLE QUINOLINE-BASED IMMUNE SYSTEM MODULATORS | IRF3, HLA-DRB1, IFNG | ALDH1A1 2789/4885HSD17B10 3710/4885KDM4E 1584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.