Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290846 | 0.86 | ALOX15 (1.00) | ALOX15ERBB2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL17283683 | 0.83 | ALOX15 (0.68) | ALOX15TDP1ERBB2ALDH1A1SMN1; SMN2 | |
| SCHEMBL28042321 | 0.81 | ERBB2 (0.55) | ALOX15ERBB2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10166458 | 0.80 | ALOX15 (0.70) | ALOX15TDP1ERBB2ALDH1A1SMN1; SMN2 | |
| SCHEMBL26867246 | 0.79 | TDP1 (0.79) | TDP1ALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL16659834 | 0.79 | TDP1 (0.79) | TDP1ALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL28439616 | 0.79 | ALDH1A1 (0.47) | ALOX15TDP1ERBB2ALDH1A1SMN1; SMN2 | |
| SCHEMBL28251777 | 0.77 | MAPT (0.57) | ALOX15TDP1ERBB2ALDH1A1SMN1; SMN2 | |
| SCHEMBL17283552 | 0.77 | ALOX15 (0.81) | ALOX15ERBB2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL3108967 | 0.76 | TDP1 (0.52) | ALOX15TDP1ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130916-B | Method for efficiently preparing NH-1,2,3 triazole compound | 江西师范大学 | 2019-03-01 | — | — | CN | disclosed |
| CN-105130916-A | Method for efficiently preparing NH-1,2,3 triazole compound | UNIV JIANGXI NORMAL | 2015-12-09 | — | — | CN | disclosed |