Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11475821 | 0.83 | KMT2A (0.54) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL13662724 | 0.82 | NOTUM (0.47) | POLBNOTUMALDH1A1TDP1TSHR | |
| SCHEMBL28870075 | 0.79 | MAPT (0.52) | POLBNOTUMALDH1A1NOS1MEN1 | |
| SCHEMBL25353365 | 0.78 | ALDH1A1 (0.39) | POLBALDH1A1TDP1NOS3NOS1 | |
| SCHEMBL44771 | 0.77 | ALDH1A1 (0.49) | NOTUMALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL16863795 | 0.77 | MAPT (0.41) | POLBALDH1A1TDP1TSHRMEN1 | |
| SCHEMBL380712 | 0.76 | L3MBTL1 (0.40) | ALDH1A1TDP1MEN1KMT2ANPC1 | |
| SCHEMBL31233837 | 0.76 | NOTUM (0.41) | POLBNOTUMALDH1A1MEN1KMT2A | |
| SCHEMBL20249597 | 0.74 | TDO2 (0.34) | ALDH1A1TDP1NOS3NOS2 | |
| SCHEMBL20242276 | 0.74 | ELOVL1 (0.40) | ALDH1A1TDP1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108477173-A | Heterocyclic compound as insecticide | 拜耳农作物科学股份公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-105101800-B | Heterocyclic Compounds as Pesticides | 拜耳农作物科学股份公司 | 2018-04-13 | — | — | CN | disclosed |
| CN-105101800-A | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG | 2015-11-25 | — | — | CN | disclosed |