SCHEMBL28042579

SCHEMBL28042579

CNC(=O)c1ccccc1-c1ccn(-c2ccccc2Cl)n1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.40
BRD4 O60885 1/20 0.40
BRD2 P25440 1/20 0.40
BRD3 Q15059 1/20 0.40
BRDT Q58F21 1/20 0.40
HSD17B3 P37058 1/20 0.39
CCKBR P32239 4/20 0.38
CCKAR P32238 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
CAPN1 P07384 1/20 0.38
ADCY10 Q96PN6 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.37
SCN9A Q15858 1/20 0.37
GAA P10253 1/20 0.37
NTRK1 P04629 1/20 0.37
ULK1 O75385 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28042524 0.83 PARP1 (0.54) PARP1CAPN1KDM4EALDH1A1SCN9A
SCHEMBL15639397 0.71 NPC1 (0.53) L3MBTL1ALDH1A1
SCHEMBL29572327 0.71 NPC1 (0.53) L3MBTL1ALDH1A1
SCHEMBL29626876 0.70 BCAT2 (0.44) PARP1CAPN1KDM4EALDH1A1
SCHEMBL6262435 0.70 DRD2 (0.54)
SCHEMBL10847700 0.69 HPGD (0.48) KDM4EALDH1A1SCN9AULK1
SCHEMBL883582 0.69 POLB (0.69) L3MBTL1KDM4EALDH1A1GAA
SCHEMBL30452120 0.69 POLB (0.69) L3MBTL1KDM4EALDH1A1GAA
SCHEMBL11410287 0.69 GAA (0.63) BRD4BRD2BRD3BRDTL3MBTL1
SCHEMBL12528566 0.69 BCHE (0.58) L3MBTL1CAPN1KDM4EALDH1A1SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105101800-A Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG 2015-11-25 CN disclosed