Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4096988 | 0.88 | ALDH1A1 (0.45) | ALDH1A1KMT2AHSD17B10KDM4EHPGD | |
| SCHEMBL1401556 | 0.83 | KDM4E (0.58) | ALDH1A1KMT2AHSD17B10KDM4EHPGD | |
| SCHEMBL2807745 | 0.83 | CA12 (0.57) | ALDH1A1KMT2AHSD17B10KDM4EHPGD | |
| SCHEMBL2229575 | 0.82 | SIRT5 (0.41) | ALDH1A1HSD17B10KDM4EL3MBTL1HDAC1 | |
| SCHEMBL18204421 | 0.81 | KDM4E (0.47) | ALDH1A1KMT2AHSD17B10KDM4EHPGD | |
| SCHEMBL4261271 | 0.80 | KMT2A (0.47) | ALDH1A1KMT2AHSD17B10KDM4EHPGD | |
| SCHEMBL1815890 | 0.80 | RAB9A (0.54) | ALDH1A1KMT2AHSD17B10KDM4EHPGD | |
| SCHEMBL19680526 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KMT2AHSD17B10KDM4EHPGD | |
| SCHEMBL31613155 | 0.79 | KMT2A (0.46) | ALDH1A1KMT2AHSD17B10KDM4EHPGD | |
| SCHEMBL30822002 | 0.79 | KMT2A (0.46) | ALDH1A1KMT2AHSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202865-B2 | Oxadiazole derivatives | MERCK SERONO SA (CH) | 2012-06-19 | — | — | US | disclosed |
| US-20100240658-A1 | Oxadiazole Derivatives | MERCK SERONO SA (CH) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240658-A1 | Oxadiazole Derivatives | OXA1L, RO60, NQO2 | ALDH1A1 516/4885KMT2A 1416/4885HSD17B10 3180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.