Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28042726 | 0.96 | PLA2G2A (0.47) | PLA2G2ATP53TSHRALDH1A1HPGD | |
| SCHEMBL28042771 | 0.94 | KMT2A (0.39) | PLA2G2ATSHRALDH1A1HPGDRXRA | |
| SCHEMBL28042914 | 0.79 | MEN1 (0.48) | TP53HPGDRXRA | |
| SCHEMBL15996999 | 0.75 | PLK1 (0.48) | PLA2G2ATP53TSHRALDH1A1HPGD | |
| SCHEMBL7995915 | 0.75 | PLA2G2A (0.56) | PLA2G2ATP53TSHRALDH1A1HPGD | |
| SCHEMBL12604610 | 0.72 | PLA2G2A (0.56) | PLA2G2ATP53TSHRALDH1A1HPGD | |
| SCHEMBL12101421 | 0.70 | PLA2G2A (0.54) | PLA2G2ATP53TSHRALDH1A1HPGD | |
| SCHEMBL2664838 | 0.70 | PLA2G2A (0.54) | PLA2G2ATP53TSHRALDH1A1HPGD | |
| SCHEMBL1108059 | 0.69 | PLA2G2A (0.66) | PLA2G2ATP53TSHRALDH1A1HPGD | |
| SCHEMBL1201538 | 0.69 | PLA2G2A (0.66) | PLA2G2ATP53TSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103265517-B | 3-substituted cumarin analog derivative and uses thereof | ZHEJIANG UNIVERSITY (CN) | 2016-01-13 | — | — | CN | disclosed |