Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28042771 | 0.80 | KMT2A (0.39) | KMT2AHPGDRXRA | |
| SCHEMBL28042730 | 0.79 | PLA2G2A (0.42) | HPGDTP53RXRA | |
| SCHEMBL28042726 | 0.78 | PLA2G2A (0.47) | MEN1KMT2AHPGDTP53 | |
| SCHEMBL793724 | 0.75 | MEN1 (0.65) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL30077214 | 0.75 | MEN1 (0.50) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL14660694 | 0.74 | MEN1 (0.63) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| Hydrochloric Acid SCHEMBL514496 | 0.74 | MEN1 (0.63) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL5838451 | 0.71 | MEN1 (0.63) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL642448 | 0.71 | MEN1 (0.63) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL17966385 | 0.71 | MEN1 (0.63) | MEN1KMT2ANR4A2NR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103265517-B | 3-substituted cumarin analog derivative and uses thereof | ZHEJIANG UNIVERSITY (CN) | 2016-01-13 | — | — | CN | disclosed |