Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28042730 | 0.94 | PLA2G2A (0.42) | PLA2G2ARXRAHPGDALDH1A1TSHR | |
| SCHEMBL28042726 | 0.93 | PLA2G2A (0.47) | KMT2APLA2G2AHPGDALDH1A1TSHR | |
| SCHEMBL28042914 | 0.80 | MEN1 (0.48) | KMT2ARXRAHPGD | |
| SCHEMBL15996999 | 0.68 | PLK1 (0.48) | PLA2G2ARXRAHPGDPOLBALDH1A1 | |
| SCHEMBL8636608 | 0.68 | SMN1; SMN2 (0.60) | KMT2AHSD17B10POLBALDH1A1TSHR | |
| SCHEMBL8934809 | 0.68 | PTGS2 (0.61) | KMT2APLA2G2AHPGDHSD17B10POLB | |
| SCHEMBL566516 | 0.67 | POLB (0.66) | KMT2AHPGDHSD17B10POLBCASP6 | |
| SCHEMBL7995915 | 0.67 | PLA2G2A (0.56) | PLA2G2AHPGDALDH1A1TSHRPTPN11 | |
| SCHEMBL16072742 | 0.66 | RARB (0.46) | KMT2APLA2G2AHPGDPOLBCASP6 | |
| SCHEMBL27491591 | 0.66 | KMT2A (0.46) | KMT2APLA2G2ARXRAPOLBCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103265517-B | 3-substituted cumarin analog derivative and uses thereof | ZHEJIANG UNIVERSITY (CN) | 2016-01-13 | — | — | CN | disclosed |