Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTR6 | P50406 | 5/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27979569 | 0.77 | DRD4 (0.47) | KDM4ELMNAMAPTSIGMAR1GAA | |
| SCHEMBL28096230 | 0.74 | SIGMAR1 (0.57) | KDM4ELMNAMAPTSIGMAR1DRD2 | |
| SCHEMBL23277150 | 0.73 | KDM4E (0.49) | KDM4ELMNAMAPTSIGMAR1DRD2 | |
| SCHEMBL27831844 | 0.73 | KDM4E (0.41) | KDM4ELMNAMAPTSIGMAR1SUV39H2 | |
| SCHEMBL27712204 | 0.70 | KDM4E (0.43) | KDM4ELMNAMAPTHTR6SIGMAR1 | |
| SCHEMBL16013186 | 0.70 | PDK4 (0.52) | HTR6 | |
| SCHEMBL27801629 | 0.70 | KDM4E (0.56) | KDM4ELMNAMAPTSIGMAR1GAA | |
| SCHEMBL27979395 | 0.69 | MEN1 (0.42) | KDM4EMAPTSIGMAR1MEN1KMT2A | |
| SCHEMBL27914131 | 0.68 | SIGMAR1 (0.57) | MAPTSIGMAR1MEN1KMT2ADRD2 | |
| SCHEMBL28108120 | 0.68 | QDPR (0.51) | KDM4EMAPTSIGMAR1SUV39H2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105051033-B | Antiviral compound | 豪夫迈·罗氏有限公司 | 2018-02-16 | — | — | CN | disclosed |
| CN-105051033-A | Antiviral compounds | HOFFMANN LA ROCHE | 2015-11-11 | — | — | CN | disclosed |