Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SCN8A | Q9UQD0 | 10/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 4/20 | 0.47 |
| ▸ | SCN1A | P35498 | 2/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31114428 | 0.87 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2SCN8AKDM4ELMNA | |
| SCHEMBL3976683 | 0.85 | SCN8A (0.44) | ALDH1A1SMN1; SMN2SCN8AKDM4ELMNA | |
| SCHEMBL17668299 | 0.83 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2SCN8AKDM4ELMNA | |
| SCHEMBL6373909 | 0.80 | ALDH1A1 (0.55) | ALDH1A1SCN8AKDM4ELMNAMEN1 | |
| SCHEMBL4382775 | 0.80 | ALDH1A1 (0.55) | ALDH1A1SCN8AKDM4ELMNAMEN1 | |
| SCHEMBL14176701 | 0.79 | SMN1; SMN2 (0.77) | ALDH1A1SMN1; SMN2SCN8ALMNAMEN1 | |
| SCHEMBL23817559 | 0.78 | ALDH1A1 (0.54) | ALDH1A1SCN8AKDM4ELMNAMEN1 | |
| SCHEMBL10768133 | 0.78 | ALDH1A1 (0.53) | ALDH1A1SCN8AKDM4ELMNAMEN1 | |
| SCHEMBL6470644 | 0.78 | ALDH1A1 (0.53) | ALDH1A1SCN8AKDM4ELMNAMEN1 | |
| SCHEMBL6928489 | 0.78 | SCN4A (0.53) | ALDH1A1SCN8AKDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473595-A | Carboxylic acid compounds in treatment of diabetes mellitus | FUJIAN HAIXI PHARMACEUTICALS CO LTD | 2016-04-06 | — | — | CN | disclosed |