Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28042959 | 0.85 | ALDH1A1 (0.53) | SCN8ASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL24629478 | 0.84 | KDM4E (0.42) | SCN8AALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL13490677 | 0.81 | HPGD (0.46) | SMN1; SMN2ALDH1A1MAPTHPGDATM | |
| SCHEMBL16954557 | 0.80 | MAPT (0.44) | SCN8AALDH1A1MAPTL3MBTL1PTGER1 | |
| SCHEMBL19456539 | 0.78 | KDM4E (0.47) | SCN8ASMN1; SMN2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL13344106 | 0.77 | GABRA1 (0.43) | SCN8ASMN1; SMN2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL31114428 | 0.77 | SMN1; SMN2 (0.44) | SCN8ASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL8166933 | 0.75 | GABRA1 (0.44) | SCN8ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13384804 | 0.73 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1MAPTHPGDPTGER1 | |
| SCHEMBL13490745 | 0.73 | L3MBTL1 (0.70) | SMN1; SMN2MAPTHPGDATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053277-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2009-04-30 | — | — | WO | disclosed |