Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PLEC | Q15149 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1067501 | 0.86 | L3MBTL1 (0.49) | LMNAADRA2AADRA2BADRA2CL3MBTL1 | |
| SCHEMBL9924430 | 0.84 | LMNA (0.38) | LMNAADRA2AADRA2BADRA2CL3MBTL1 | |
| SCHEMBL23906795 | 0.83 | LMNA (0.48) | LMNAADRA2AADRA2BADRA2CL3MBTL1 | |
| SCHEMBL10796901 | 0.83 | ADRA2A (0.49) | LMNAADRA2AADRA2BADRA2CL3MBTL1 | |
| SCHEMBL27701197 | 0.80 | CA1 (0.50) | LMNAADRA2AADRA2BADRA2CL3MBTL1 | |
| SCHEMBL27525281 | 0.78 | THRA (0.48) | ADRA2AADRA2BADRA2CHTR1ATHRB | |
| SCHEMBL7535391 | 0.77 | IDO1 (0.48) | LMNAIDO1MAPTALDH1A1FFAR4 | |
| SCHEMBL7101261 | 0.77 | LMNA (0.43) | LMNAL3MBTL1 | |
| SCHEMBL13086759 | 0.77 | CYP1A2 (0.41) | LMNAADRA2BL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL8218163 | 0.77 | ADRA2A (0.48) | LMNAADRA2AADRA2BADRA2CL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105051048-A | 1-hydroxy-benzoxaboroles as antiparasitic agents | LILLY CO ELI | 2015-11-11 | — | — | CN | disclosed |