Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 4/20 | 0.42 |
| ▸ | PGK2 | P07205 | 4/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KYNU | Q16719 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13959620 | 0.84 | PRSS1 (0.41) | PGK1PGK2PNMTHRH1NOS1 | |
| SCHEMBL17277380 | 0.83 | CYP3A4 (0.41) | PGK1PGK2PNMTHRH1NOS1 | |
| SCHEMBL27836303 | 0.83 | PNMT (0.39) | PGK1PGK2PNMTHRH1KYNU | |
| SCHEMBL612881 | 0.81 | MAOA (0.46) | HRH1NOS1NOS2 | |
| SCHEMBL10287581 | 0.81 | MAOA (0.46) | HRH1NOS1NOS2 | |
| SCHEMBL611352 | 0.80 | HRH1 (0.44) | HRH1NOS1NOS2 | |
| SCHEMBL10287473 | 0.80 | NOS1 (0.39) | PGK1PGK2PNMTNOS1NOS2 | |
| SCHEMBL3180843 | 0.80 | L3MBTL1 (0.40) | PGK1PGK2PNMTKYNUL3MBTL1 | |
| SCHEMBL612176 | 0.79 | MAOA (0.50) | HRH1 | |
| SCHEMBL3227928 | 0.79 | AOC3 (0.40) | PGK1PGK2PNMTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102197023-B | Compounds for the treatment of ophthalmic diseases and disorders | ACUCELA INC. (US) | 2015-12-16 | — | — | CN | disclosed |