Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501660 | 0.72 | SLC18A3 (0.42) | SMN1; SMN2OPRL1KMT2ANPSR1CCR2 | |
| SCHEMBL27890446 | 0.71 | CYP3A4 (0.46) | SMN1; SMN2OPRL1OPRM1KMT2A | |
| SCHEMBL28652818 | 0.70 | TRPA1 (0.33) | — | |
| SCHEMBL30999500 | 0.69 | DRD2 (0.37) | — | |
| SCHEMBL28338402 | 0.69 | TDP1 (0.40) | ALDH1A1KMT2A | |
| SCHEMBL11039283 | 0.68 | CYP3A4 (0.43) | SMN1; SMN2OPRL1OPRM1KMT2A | |
| SCHEMBL27800697 | 0.68 | CYP3A4 (0.43) | OPRL1OPRM1KMT2A | |
| SCHEMBL9862085 | 0.67 | IDH1 (0.36) | — | |
| Bromide SCHEMBL11037477 | 0.67 | CYP3A4 (0.42) | SMN1; SMN2OPRL1OPRM1KMT2A | |
| SCHEMBL27893441 | 0.67 | KDM4E (0.42) | OPRL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103172512-B | A group of compounds with similar cajanin structure, preparation method and application | 中国医学科学院医药生物技术研究所 | 2016-08-03 | — | — | CN | disclosed |
| CN-105030750-A | Application of longistyline structural analogues in prevention of hepatitis C virus and acquired immune deficiency syndrome (AIDS) virus | INST MED BIOTECHNOLOGY CAMS | 2015-11-11 | — | — | CN | disclosed |