SCHEMBL2804394

SCHEMBL2804394

CC(C)(C)O[SiH](C(C)(C)C)C(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL703026 0.69 TSHR (0.31) TSHRTDP1ALDH1A1
SCHEMBL919318 0.67
SCHEMBL273377 0.67 ALDH1A1 (0.36) TSHRTDP1ALDH1A1
SCHEMBL16588443 0.67
Ethane SCHEMBL5834783 0.67
Ethylene SCHEMBL5833978 0.65
SCHEMBL474754 0.64 ALDH1A1 (0.33) TSHRTDP1ALDH1A1
SCHEMBL190883 0.64
SCHEMBL4083638 0.64 ALDH1A1 (0.33) ALDH1A1
SCHEMBL13089616 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2168757-B1 METHOD OF MANUFACTURING A PLASTIC LENS HOYA CORP (JP) 2015-04-29 EP disclosed
US-20100239776-A1 METHOD FOR PRODUCING PLASTIC LENS HOYA CORPORATION (JP) 2010-09-23 US disclosed
EP-2168757-A1 METHOD FOR PRODUCING PLASTIC LENS Hoya Corporation (JP) 2010-03-31 EP disclosed