Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CRHBP | P24387 | 2/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13285509 | 0.89 | CYP2C19 (0.50) | ALDH1A1POLBSMN1; SMN2HTTLMNA | |
| SCHEMBL27568201 | 0.88 | MEN1 (0.51) | ALDH1A1CRHBPCRHR2LMNAMAPT | |
| SCHEMBL28095287 | 0.88 | CNR1 (0.49) | ALDH1A1SMN1; SMN2CRHBPCRHR2MAPT | |
| SCHEMBL11604190 | 0.82 | SMN1; SMN2 (0.43) | ALDH1A1POLBSMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL28292761 | 0.78 | TAAR1 (0.52) | ALDH1A1POLBSMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL9285815 | 0.78 | SMN1; SMN2 (0.56) | ALDH1A1POLBSMN1; SMN2HTTLMNA | |
| SCHEMBL9290103 | 0.76 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL5514976 | 0.75 | MAPT (0.48) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL2308839 | 0.74 | MAPT (0.52) | ALDH1A1SMN1; SMN2HTTMAPTMEN1 | |
| SCHEMBL13282525 | 0.74 | CNR2 (0.48) | POLBMAPTMEN1KMT2AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143281-B | Tridentate nitrogen-based ligands for olefin polymerization catalysts | 尤尼威蒂恩技术有限责任公司 | 2018-06-01 | — | — | CN | disclosed |
| CN-105143281-A | Tridentate nitrogen-based ligands for olefin polymerization catalysts | UNIVATION TECH LLC | 2015-12-09 | — | — | CN | disclosed |