Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | CTSC | P53634 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28511390 | 0.86 | CHRM2 (0.37) | CHRM2CHRM1CHRM3DPP4DPP8 | |
| SCHEMBL7359958 | 0.85 | MAPK1 (0.36) | CHRM2CHRM1CHRM3DPP4HRH3 | |
| SCHEMBL22152561 | 0.85 | MAPK1 (0.36) | CHRM2CHRM1CHRM3DPP4HRH3 | |
| SCHEMBL7379626 | 0.85 | MAPK1 (0.36) | CHRM2CHRM1CHRM3DPP4HRH3 | |
| SCHEMBL29308170 | 0.82 | DPP4 (0.41) | CHRM2CHRM1CHRM3DPP4DPP8 | |
| SCHEMBL21673908 | 0.82 | DPP4 (0.41) | CHRM2CHRM1CHRM3DPP4DPP8 | |
| SCHEMBL695946 | 0.82 | DPP4 (0.41) | CHRM2CHRM1CHRM3DPP4DPP8 | |
| SCHEMBL4017978 | 0.82 | DPP4 (0.41) | CHRM2CHRM1CHRM3DPP4DPP8 | |
| SCHEMBL28146362 | 0.82 | DPP4 (0.41) | CHRM2CHRM1CHRM3DPP4DPP8 | |
| SCHEMBL28044033 | 0.81 | CHRM2 (0.33) | CHRM2CHRM1CHRM3HRH3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301279-B2 | Piperidine carboxamide compound, preparation method, and use thereof | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) | 2019-05-28 | — | — | US | disclosed |
| US-20180044321-A1 | NOVEL PIPERIDINE CARBOXAMIDE COMPOUND, PREPARATION METHOD, AND USE THEREOF | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) | 2018-02-15 | — | — | US | disclosed |
| EP-1757594-A1 | QUINAZOLINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044321-A1 | NOVEL PIPERIDINE CARBOXAMIDE COMPOUND, PREPARATION METHOD, AND USE THEREOF | HSF1, HSP90AB1, HEATR1 | CHRM2 4098/4885CHRM1 4510/4885CHRM3 4590/4885 |
| US-10301279-B2 | Piperidine carboxamide compound, preparation method, and use thereof | HSF1, HSP90AB1, HSPD1 | CHRM2 4296/4885CHRM1 4616/4885CHRM3 4629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.