Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27634990 | 0.82 | SIGMAR1 (0.46) | SIGMAR1HTR1AKDM4EMAPTLMNA | |
| SCHEMBL2394181 | 0.81 | NAMPT (0.58) | SIGMAR1KDM4EMAPTLMNAMEN1 | |
| SCHEMBL15952018 | 0.80 | QDPR (0.48) | MAPTMEN1KMT2A | |
| SCHEMBL27195853 | 0.79 | QDPR (0.59) | LMNA | |
| SCHEMBL15984674 | 0.79 | TDP1 (0.47) | MAPTMEN1KMT2A | |
| SCHEMBL27979569 | 0.77 | DRD4 (0.47) | SIGMAR1KDM4EMAPTLMNAMEN1 | |
| SCHEMBL27914131 | 0.77 | SIGMAR1 (0.57) | SIGMAR1HTR1AMAPTMEN1KMT2A | |
| SCHEMBL28096230 | 0.77 | SIGMAR1 (0.57) | SIGMAR1HTR1AKDM4EMAPTLMNA | |
| SCHEMBL27801629 | 0.77 | KDM4E (0.56) | SIGMAR1HTR1AKDM4EMAPTLMNA | |
| SCHEMBL20582537 | 0.76 | PPARG (0.45) | SIGMAR1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073730-A | monocyclic pyridine derivatives | WEI CAIR | 2015-11-18 | — | — | CN | disclosed |