Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP9X | Q93008 | 3/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18760087 | 0.86 | USP9X (0.38) | USP9XSLC6A9 | |
| SCHEMBL15524327 | 0.80 | KDM1A (0.39) | USP9XKCNH2 | |
| SCHEMBL20483601 | 0.75 | DPP4 (0.40) | USP9XSLC6A9KCNH2 | |
| SCHEMBL17380568 | 0.74 | HDAC1 (0.39) | NAMPT | |
| SCHEMBL2364142 | 0.73 | DPP4 (0.41) | USP9XSLC6A9NAMPTKCNH2 | |
| SCHEMBL15152898 | 0.73 | PDK2 (0.54) | SLC6A9PDK2KCNH2 | |
| SCHEMBL17202438 | 0.71 | DPP4 (0.39) | NAMPTPDK2 | |
| SCHEMBL25500318 | 0.71 | HDAC8 (0.39) | USP9XPDK2KCNH2 | |
| SCHEMBL28877856 | 0.70 | HDAC1 (0.42) | USP9XSLC6A9NAMPTPDK2 | |
| SCHEMBL15152954 | 0.70 | DPP4 (0.39) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294694-A | Amino hexatomic ring derivative and application thereof to medicine | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2016-02-03 | — | — | CN | disclosed |