SCHEMBL28045052

SCHEMBL28045052

CCO[Si](OCC)(OCCCCBr)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.31
LTA4H P09960 1/20 0.31
TBXAS1 P24557 2/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
PTGS2 P35354 2/20 0.30
SOAT1 P35610 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
DUT P33316 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28045085 0.89 LMNA (0.34) KCNA3LTA4HSOAT1
SCHEMBL4262217 0.88 TDP1 (0.30) TDP1
SCHEMBL27943310 0.86 LTA4H (0.43) LTA4HSOAT1
SCHEMBL28045151 0.85 LTA4H (0.33) LTA4HDUT
SCHEMBL35139 0.85 SOAT1 (0.42) LTA4HSOAT1
SCHEMBL17391462 0.85 SOAT1 (0.42) LTA4HSOAT1
SCHEMBL28592042 0.85 SOAT1 (0.42) LTA4HSOAT1
SCHEMBL17391469 0.85 SOAT1 (0.42) LTA4HSOAT1
SCHEMBL3713762 0.84 LTA4H (0.43) LTA4HL3MBTL1SOAT1TDP1
SCHEMBL28662102 0.83 MAOA (0.36) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105163853-A Method for manufacturing catalyst for synthesizing cyclic carbonate MARUZEN PETROCHEM CO LTD 2015-12-16 CN disclosed
CN-105163854-A Method for producing catalyst for synthesizing cyclic carbonate NAT INST OF ADVANCED IND SCIEN 2015-12-16 CN disclosed
CN-105121013-A Method for producing catalyst for cyclic carbonate synthesis MARUZEN PETROCHEM CO LTD 2015-12-02 CN disclosed