SCHEMBL28045151

SCHEMBL28045151

CCCO[Si](OCCC)(OCCCBr)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.33
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
DUT P33316 1/20 0.31
ALDH1A1 P00352 2/20 0.30
HPGD P15428 1/20 0.30
TOP2A P11388 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28045085 0.93 LMNA (0.34) LTA4HLMNAMEN1KMT2AALDH1A1
SCHEMBL9228586 0.87 LTA4H (0.44) LTA4HLMNAMEN1KMT2AALDH1A1
SCHEMBL105659 0.87 LMNA (0.39) LTA4HLMNAMEN1KMT2AALDH1A1
SCHEMBL28045052 0.85 KCNA3 (0.31) LTA4HDUT
SCHEMBL431649 0.83 LTA4H (0.47) LTA4HALDH1A1
SCHEMBL28808583 0.83 MEN1 (0.36) LTA4HLMNAMEN1KMT2AALDH1A1
SCHEMBL61765 0.83 HTR1B (0.34) LTA4HLMNAMEN1KMT2A
SCHEMBL19809137 0.83 LMNA (0.36) LTA4HLMNAMEN1KMT2ADUT
SCHEMBL7863713 0.82 LMNA (0.36) LTA4HLMNAMEN1KMT2AALDH1A1
SCHEMBL27975354 0.82 LMNA (0.36) LTA4HLMNAMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105163853-A Method for manufacturing catalyst for synthesizing cyclic carbonate MARUZEN PETROCHEM CO LTD 2015-12-16 CN disclosed
CN-105163854-A Method for producing catalyst for synthesizing cyclic carbonate NAT INST OF ADVANCED IND SCIEN 2015-12-16 CN disclosed
CN-105121013-A Method for producing catalyst for cyclic carbonate synthesis MARUZEN PETROCHEM CO LTD 2015-12-02 CN disclosed