Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23778979 | 0.98 | OPRM1 (0.46) | OPRM1OPRL1OPRK1VNN1HDAC6 | |
| SCHEMBL29010349 | 0.93 | P2RX7 (0.42) | OPRM1OPRL1OPRK1VNN1HDAC6 | |
| SCHEMBL3667011 | 0.91 | P2RX7 (0.41) | OPRM1OPRL1OPRK1VNN1HDAC6 | |
| SCHEMBL3407459 | 0.87 | VNN1 (0.40) | OPRM1OPRL1OPRK1VNN1HDAC6 | |
| Hydrochloric Acid SCHEMBL5874164 | 0.82 | VNN1 (0.38) | VNN1HDAC6SMN1; SMN2P2RX7 | |
| Hydrochloric Acid SCHEMBL5874186 | 0.82 | VNN1 (0.38) | VNN1HDAC6SMN1; SMN2P2RX7 | |
| SCHEMBL12259419 | 0.80 | VNN1 (0.44) | OPRM1OPRL1OPRK1VNN1HDAC6 | |
| SCHEMBL29438096 | 0.79 | VNN1 (0.52) | VNN1SMN1; SMN2P2RX7 | |
| SCHEMBL19322923 | 0.79 | VNN1 (0.52) | VNN1SMN1; SMN2P2RX7 | |
| SCHEMBL3409814 | 0.79 | ALDH1A1 (0.51) | OPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105307651-A | Thiazole compound and application thereof | ABBVIE INC | 2016-02-03 | — | — | CN | disclosed |