Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 4/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL981676 | 0.92 | LMNA (0.55) | THRBMEN1KMT2ALMNABLM | |
| Pyrene SCHEMBL18343705 | 0.87 | KMT2A (0.65) | THRBMEN1KMT2ALMNABLM | |
| SCHEMBL10549144 | 0.84 | POLB (0.51) | THRBMEN1KMT2ALMNABLM | |
| SCHEMBL17422072 | 0.83 | ALDH1A1 (0.46) | THRBMEN1KMT2ALMNABLM | |
| SCHEMBL29953603 | 0.82 | HSD17B10 (0.56) | MEN1KMT2ALMNATDP1ALDH1A1 | |
| SCHEMBL5276864 | 0.81 | MEN1 (0.48) | THRBMEN1KMT2ALMNABLM | |
| SCHEMBL3832835 | 0.81 | ALDH1A1 (0.58) | THRBMEN1KMT2ALMNABLM | |
| SCHEMBL11932607 | 0.81 | MEN1 (0.44) | THRBMEN1KMT2ALMNABLM | |
| SCHEMBL20974586 | 0.81 | CYP2A6 (0.52) | THRBMEN1KMT2ALMNABLM | |
| SCHEMBL9099949 | 0.81 | ERN1 (0.59) | THRBMEN1KMT2ALMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557565-B2 | Degradation of polycyclic aromatic hydrocarbons to render them available for biodegradation | WAVREK DAVID (US) | 2013-10-15 | — | — | US | disclosed |
| US-8298814-B1 | Degradation of polycyclic aromatic hydrocarbons | Wavrek, David A. (US) | 2012-10-30 | — | — | US | disclosed |
| US-7745819-B2 | Pyrene derivatives and organic electronic device using pyrene derivatives | LG CHEM. LTD. (KR) | 2010-06-29 | — | — | US | disclosed |
| US-20080242875-A1 | DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS TO RENDER THEM AVAILABLE FOR BIODEGRADATION | HONG P K ANDY | 2008-10-02 | — | — | US | disclosed |
| EP-1230400-B1 | DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS | UNIV UTAH RES FOUND (US) | 2008-09-24 | — | — | EP | disclosed |
| EP-1230400-A1 | DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS | University of Utah Research Foundation (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001032936-A1 | DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2001-05-10 | — | — | WO | disclosed |
| US-4017313-A | Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242875-A1 | DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS TO RENDER THEM AVAILABLE FOR BIODEGRADATION | PAH, AHR, TDO2 | THRB 2054/4885MEN1 2632/4885KMT2A 4179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.