Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | EIF4E | P06730 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6313832 | 0.88 | ALDH1A1 (0.53) | TDP1ATMTAAR1MAPTMEN1 | |
| SCHEMBL721310 | 0.85 | TDP1 (0.71) | TDP1ATMTAAR1MAPTMEN1 | |
| SCHEMBL29655008 | 0.85 | TDP1 (0.71) | TDP1ATMTAAR1MAPTMEN1 | |
| SCHEMBL28106852 | 0.85 | SMN1; SMN2 (0.49) | TDP1ATMTAAR1MAPTMEN1 | |
| SCHEMBL3976788 | 0.82 | TDP1 (0.64) | TDP1ATMMAPTMEN1POLB | |
| SCHEMBL5195739 | 0.81 | DCLRE1B (0.56) | TDP1ESR2FBP1TSHRCRHBP | |
| SCHEMBL1663325 | 0.81 | CRHBP (0.63) | TDP1MAPTMEN1POLBKMT2A | |
| SCHEMBL12812871 | 0.80 | TAAR1 (0.53) | TAAR1MAPTMEN1POLBKMT2A | |
| SCHEMBL14786422 | 0.79 | TDP1 (0.45) | TDP1ATMTAAR1MAPTMEN1 | |
| Benzene SCHEMBL27678346 | 0.79 | TDP1 (0.67) | TDP1ATMMAPTCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189454-A | Phenyl derivative | ONO PHARMACEUTICAL CO | 2015-12-23 | — | — | CN | disclosed |