Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL73388 | 0.83 | MAPT (0.48) | NPC1MAPTKDM4ETDP1POLB | |
| Phosphoric Acid SCHEMBL28045407 | 0.82 | MAPT (0.48) | NPC1MAPTKDM4ETDP1POLB | |
| Sulfuric Acid SCHEMBL7599722 | 0.82 | CA1 (0.54) | NPC1MAPTKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1712305 | 0.80 | MAPT (0.46) | NPC1MAPTKDM4ETDP1POLB | |
| Nitric Acid SCHEMBL28280438 | 0.78 | MAPT (0.54) | NPC1MAPTKDM4ETDP1POLB | |
| Phenylhydrazine SCHEMBL19875575 | 0.78 | IDO1 (0.74) | MAPTKDM4ETDP1LMNAL3MBTL1 | |
| SCHEMBL28375697 | 0.77 | CA1 (0.43) | NPC1MAPTKDM4ETDP1POLB | |
| Oxalic Acid SCHEMBL20984619 | 0.77 | MAOA (0.50) | NPC1MAPTKDM4ETDP1POLB | |
| Oxalic Acid SCHEMBL20984984 | 0.77 | TSHR (0.55) | NPC1MAPTKDM4ETDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272874-A | 4-chlorophenylhydrazine oxalate preparation method | TIANJIN CHEM REAGENT RES INST | 2016-01-27 | — | — | CN | claimed |
| CN-107663160-B | A kind of continuous flow synthesis technology of 4- chlorobenzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-107663160-A | A kind of continuous stream synthesis technique of 4 chlorobenzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |
| CN-105272874-A | 4-chlorophenylhydrazine oxalate preparation method | TIANJIN CHEM REAGENT RES INST | 2016-01-27 | — | — | CN | disclosed |
| CN-105272874-A | 4-chlorophenylhydrazine oxalate preparation method | TIANJIN CHEM REAGENT RES INST | 2016-01-27 | — | — | CN | disclosed |
| CN-105272874-A | 4-chlorophenylhydrazine oxalate preparation method | TIANJIN CHEM REAGENT RES INST | 2016-01-27 | — | — | CN | disclosed |