Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.48 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.46 |
| ▸ | MAOA known ✓ | P21397 | 2/20 | 0.45 |
| ▸ | MAOB known ✓ | P27338 | 2/20 | 0.45 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL1712305 | 0.92 | MAPT (0.46) | MAPTKDM4ELMNATDP1CYP1A2 | |
| Hydrochloric Acid SCHEMBL4375181 | 0.86 | MAOA (0.56) | MAPTKDM4ECYP1A2CYP2D6CYP2C9 | |
| Phosphoric Acid SCHEMBL28045407 | 0.83 | MAPT (0.48) | MAPTKDM4ELMNATDP1PTGS2 | |
| SCHEMBL31332184 | 0.83 | PTGIR (0.49) | MAPTKDM4ELMNATDP1CYP1A2 | |
| Oxalic Acid SCHEMBL28045429 | 0.83 | NPC1 (0.54) | MAPTKDM4ELMNATDP1CYP1A2 | |
| SCHEMBL28375697 | 0.83 | CA1 (0.43) | MAPTKDM4ELMNATDP1CYP1A2 | |
| Sulfuric Acid SCHEMBL7599722 | 0.83 | CA1 (0.54) | MAPTKDM4ELMNANPC1CA1 | |
| SCHEMBL7412496 | 0.83 | MAOA (0.58) | CA2MAOAMAOBCA9CA14 | |
| SCHEMBL218054 | 0.80 | TDP1 (0.67) | MAPTKDM4ELMNATDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036612-A | Synthesis method of 1- (4-chlorophenyl) pyrazolidine-3-ketone | 新乡市金牛精细化工有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-120006303-A | Method for inhibiting poisoning of exchange membrane in one-pot production of p-chlorophenylhydrazine | 厦门大学 | 2025-05-16 | — | — | CN | claimed |
| CN-119684213-A | Preparation method and control method of 2- [ (N-p-chlorophenyl) -3-pyrazoloxymethyl ] nitrobenzene isomer | 江苏丰山生化科技有限公司 | 2025-03-25 | — | — | CN | claimed |
| CN-115417818-B | Synthesis method of 1- (4-chlorophenyl) pyrazolidine-3-ketone | 江苏七洲绿色科技研究院有限公司 | 2024-10-15 | — | — | CN | claimed |
| CN-114276305-B | Trisubstituted phenyl-1, 2, 4-triazole derivative, preparation method thereof and application thereof in treatment of neuronal injury | 中山大学 | 2023-11-17 | — | — | CN | claimed |
| CN-112354495-B | Continuous flow reaction system and method for parachlorophenylhydrazine hydrochloride | 上海惠和化德生物科技有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-112225677-B | P-chlorophenylhydrazine hydrochloride reaction system and method | 上海惠和化德生物科技有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-112521290-B | Intermediate product beta-amino ketone alkene compound and method for synthesizing fluoroalkyl pyrazole compound by using intermediate product beta-amino ketone alkene compound | 江西师范大学 | 2023-07-04 | — | — | CN | claimed |
| CN-115417818-A | Synthesis method of 1- (4-chlorphenyl) pyrazolidin-3-ketone | 江苏七洲绿色科技研究院有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-114813984-A | Detection method of hydrochloride sample containing p-chlorophenylhydrazine | 上海素馨化工科技有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-106749288-A | N (substituted benzene) base Bi Zuo Ji fraxinellones analog derivative, its preparation method and application | 郑州大学 | 2017-05-31 | — | — | CN | claimed |
| WO-2016113741-A1 | PROCESS FOR PREPARING 1-(4-CHLOROPHENYL)-3-[(2-NITROPHENYL)METHOXY]-1H-PYRAZOLE | ADAMA MAKHTESHIM LTD. (IL) | 2016-07-21 | — | — | WO | claimed |
| CN-103768754-A | Fire-extinguishment composition containing unsaturated hydrocarbon compounds and derivatives thereof | XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY | 2014-05-07 | — | — | CN | claimed |
| WO-2008056377-A2 | POLYMORPHIC FORMS OF RIMONABANT | CADILA HEALTHCARE LIMITED (IN) | 2008-05-15 | — | — | WO | claimed |
| EP-0918052-B1 | Improved polymeric mdi color | BAYER AG (US) | 2003-05-28 | — | — | EP | claimed |
| CN-1234021-A | Synthesis of a hydrazone beta-ketoester by reaction with a diazo ester | MONSANTO CO (US) | 1999-11-03 | — | — | CN | claimed |
| US-5942151-A | PREVENTING THE DISCOLORATION OF PRODUCING POLYMETHYLENEPOLYPHENYLENE POLYISOCYANATE BY ADDING AN ADDITIVE HYDRAZINE OR A HYDRAZINE DERIVATIVE | BAYER CORPORATION (US) | 1999-08-24 | — | — | US | claimed |
| EP-0923540-A1 | SYNTHESIS OF A HYDRAZONE BETA-KETO ESTER BY THE REACTION WITH A DIAZO ESTER | MONSANTO COMPANY (US) | 1999-06-23 | — | — | EP | claimed |
| EP-0918052-A1 | Improved polymeric mdi color | Bayer Corporation (US) | 1999-05-26 | — | — | EP | claimed |
| WO-1998008807-A1 | SYNTHESIS OF A HYDRAZONE β-KETO ESTER BY THE REACTION WITH A DIAZO ESTER | MONSANTO COMPANY (US) | 1998-03-05 | — | — | WO | claimed |