Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,4-Dichlorobenzene SCHEMBL29002852 | 0.82 | FBP1 (0.52) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7843 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL73388 | 0.79 | MAPT (0.48) | MAPTMEN1KMT2AALDH1A1LMNA | |
| Nitric Acid SCHEMBL20984537 | 0.79 | MEN1 (0.44) | MAPTMEN1KMT2AALDH1A1LMNA | |
| Nitric Acid SCHEMBL20984226 | 0.79 | ALDH1A1 (0.45) | MAPTMEN1KMT2AALDH1A1LMNA | |
| Nitric Acid SCHEMBL20984121 | 0.79 | MEN1 (0.57) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| Phenylhydrazine SCHEMBL20984717 | 0.78 | LMNA (0.64) | MAPTMEN1KMT2AALDH1A1LMNA | |
| Oxalic Acid SCHEMBL28045429 | 0.78 | NPC1 (0.54) | MAPTMEN1KMT2AALDH1A1LMNA | |
| Sulfuric Acid SCHEMBL7599722 | 0.78 | CA1 (0.54) | MAPTMEN1KMT2AALDH1A1LMNA | |
| Phosphoric Acid SCHEMBL28045407 | 0.78 | MAPT (0.48) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663160-B | A kind of continuous flow synthesis technology of 4- chlorobenzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-107663160-B | A kind of continuous flow synthesis technology of 4- chlorobenzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-107663160-A | A kind of continuous stream synthesis technique of 4 chlorobenzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |