Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL73388 | 0.83 | MAPT (0.48) | MAPTALDH1A1KDM4ENPC1LMNA | |
| Sulfuric Acid SCHEMBL7599722 | 0.82 | CA1 (0.54) | MAPTALDH1A1KDM4ENPC1LMNA | |
| Oxalic Acid SCHEMBL28045429 | 0.82 | NPC1 (0.54) | MAPTALDH1A1KDM4ENPC1LMNA | |
| Hydrochloric Acid SCHEMBL1712305 | 0.80 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1LMNA | |
| 1,4-Dichlorobenzene SCHEMBL28425304 | 0.80 | LMNA (0.57) | MAPTALDH1A1KDM4ELMNAL3MBTL1 | |
| Phosphoric Acid SCHEMBL29102150 | 0.79 | CA1 (0.52) | MAPTALDH1A1KDM4ENPC1LMNA | |
| Nitric Acid SCHEMBL28280438 | 0.78 | MAPT (0.54) | MAPTALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL28375697 | 0.77 | CA1 (0.43) | MAPTALDH1A1KDM4ENPC1LMNA | |
| Phosphoric Acid SCHEMBL20985041 | 0.77 | CA12 (0.53) | ALDH1A1NPC1LMNACA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663160-B | A kind of continuous flow synthesis technology of 4- chlorobenzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-105272875-A | 4-chlorophenylhydrazine phosphate preparation method | TIANJIN CHEM REAGENT RES INST | 2016-01-27 | — | — | CN | claimed |
| CN-107663160-B | A kind of continuous flow synthesis technology of 4- chlorobenzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-107663160-A | A kind of continuous stream synthesis technique of 4 chlorobenzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |
| CN-105272875-A | 4-chlorophenylhydrazine phosphate preparation method | TIANJIN CHEM REAGENT RES INST | 2016-01-27 | — | — | CN | disclosed |
| CN-105272875-A | 4-chlorophenylhydrazine phosphate preparation method | TIANJIN CHEM REAGENT RES INST | 2016-01-27 | — | — | CN | disclosed |
| CN-105272875-A | 4-chlorophenylhydrazine phosphate preparation method | TIANJIN CHEM REAGENT RES INST | 2016-01-27 | — | — | CN | disclosed |