Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6735515 | 0.85 | PKM (0.69) | ALOX15GAAPKMHSD17B10L3MBTL1 | |
| SCHEMBL24142017 | 0.81 | NPSR1 (0.55) | ALOX15GAAPKMHSD17B10L3MBTL1 | |
| SCHEMBL1484339 | 0.80 | L3MBTL1 (0.50) | ALOX15GAAPKMHSD17B10L3MBTL1 | |
| SCHEMBL27877799 | 0.80 | L3MBTL1 (0.50) | ALOX15GAAPKMHSD17B10L3MBTL1 | |
| SCHEMBL70027 | 0.80 | NPSR1 (0.67) | HSD17B10L3MBTL1TDP1NPSR1LMNA | |
| SCHEMBL24188302 | 0.79 | HSD17B10 (0.67) | ALOX15GAAPKMHSD17B10L3MBTL1 | |
| SCHEMBL380561 | 0.78 | L3MBTL1 (0.49) | ALOX15GAAPKMHSD17B10L3MBTL1 | |
| SCHEMBL12009447 | 0.78 | GAA (0.64) | ALOX15GAAPKMHSD17B10LMNA | |
| SCHEMBL277203 | 0.76 | LMNA (0.58) | GAAL3MBTL1TDP1NPSR1LMNA | |
| SCHEMBL10519422 | 0.75 | GSK3B (0.61) | ALOX15GAAPKMHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111197-A | Synthesis methods of raltitrexed | SHANGHAI DINGYA PHARMACEUTICAL CHEMICALS CO LTD | 2015-12-02 | — | — | CN | disclosed |