SCHEMBL28045932

SCHEMBL28045932

CCc1cccc(CC)c1C1=C(c2c(CC)cccc2CC)C(=O)NC1=O

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.43
GABRB2 P47870 4/20 0.43
PDK2 Q15119 2/20 0.43
DAO P14920 3/20 0.37
NPEPPS P55786 1/20 0.37
DDO Q99489 1/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
GSK3B P49841 1/20 0.36
MGLL Q99685 1/20 0.35
PTGS2 P35354 2/20 0.35
CYP2D6 P10635 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
PARP1 P09874 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28045936 0.91 PDK2 (0.38) GABRA1GABRB2PDK2DAONPEPPS
SCHEMBL3677689 0.88 PDK2 (0.39) GABRA1GABRB2PDK2DAONPEPPS
SCHEMBL2408327 0.79 KDM4E (0.49) GABRA1GABRB2PDK2MEN1MAPT
SCHEMBL24673381 0.76 CASP3 (0.51) PDK2DAOGSK3BCYP2D6PARP1
SCHEMBL1871243 0.74 CES1 (0.56) GABRA1GABRB2PDK2DAOMEN1
SCHEMBL28552958 0.73 DAO (0.45) DAOGSK3BPTGS2HTR2AHTR2C
SCHEMBL3677437 0.72 PDK2 (0.39) GABRA1GABRB2PDK2DAONPEPPS
SCHEMBL8194264 0.71 KDM4E (0.42) PDK2DAOMEN1MAPTKMT2A
SCHEMBL29198937 0.71 PDK2 (0.40) GABRA1GABRB2PDK2DAONPEPPS
SCHEMBL9980565 0.69 KDM4E (0.43) GABRA1GABRB2PDK2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105143368-A Antifouling paint composition, antifouling paint film, antifouling substrate, and method for manufacturing antifouling substrate CHUGOKU MARINE PAINTS 2015-12-09 CN disclosed