SCHEMBL28045936

SCHEMBL28045936

CCc1cccc(CN)c1C1=C(c2c(CC)cccc2CN)C(=O)NC1=O

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.38
GABRA1 P14867 3/20 0.36
GABRB2 P47870 3/20 0.36
PNMT P11086 1/20 0.34
PRKCB P05771 5/20 0.34
PRKCA P17252 5/20 0.34
DAO P14920 3/20 0.33
NPEPPS P55786 1/20 0.33
DDO Q99489 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
PRKCD Q05655 2/20 0.32
PRKCH P24723 1/20 0.32
PRKCE Q02156 1/20 0.32
PRKCQ Q04759 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28045932 0.91 GABRA1 (0.43) PDK2GABRA1GABRB2DAONPEPPS
SCHEMBL3677689 0.80 PDK2 (0.39) PDK2GABRA1GABRB2PRKCBDAO
SCHEMBL1014384 0.74 GSK3B (0.46) PNMTMEN1MAPTKMT2A
SCHEMBL28742527 0.73 PNMT (0.38) GABRA1GABRB2PNMT
Ethane SCHEMBL27964013 0.73 DPP4 (0.47) PNMTPRKCBPRKCAPRKCDPRKCH
SCHEMBL2408327 0.72 KDM4E (0.49) PDK2GABRA1GABRB2MEN1MAPT
SCHEMBL28552958 0.70 DAO (0.45) PRKCBDAO
SCHEMBL24673381 0.69 CASP3 (0.51) PDK2DAO
SCHEMBL8194264 0.68 KDM4E (0.42) PDK2DAOMEN1MAPTKMT2A
SCHEMBL28339838 0.68 SMN1; SMN2 (0.41) PRKCBPRKCADAOMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106939132-A Antifouling paint compositions and application thereof 中国涂料株式会社 2017-07-11 CN claimed
CN-107022273-A Epoxy resin anticorrosive coating composition and anticorrosion film, stacking antifouling coat, antifouling base material and its manufacture method 中国涂料株式会社 2017-08-08 CN disclosed
CN-106939132-A Antifouling paint compositions and application thereof 中国涂料株式会社 2017-07-11 CN disclosed
CN-106905802-A Antifouling paint compositions and the coated article with its film 关西涂料株式会社 2017-06-30 CN disclosed
CN-106164189-A Its coated article of antifouling paint compositions and application 关西涂料株式会社 2016-11-23 CN disclosed
CN-105143368-A Antifouling paint composition, antifouling paint film, antifouling substrate, and method for manufacturing antifouling substrate CHUGOKU MARINE PAINTS 2015-12-09 CN disclosed