Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922520 | 0.80 | DPP4 (0.42) | CYP3A4L3MBTL1KMT2AMAPTNPSR1 | |
| SCHEMBL25233643 | 0.80 | ALDH1A1 (0.39) | PLAUKMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL18497250 | 0.79 | SETDB1 (0.47) | L3MBTL1MAPTALDH1A1NPSR1POLB | |
| SCHEMBL27842668 | 0.76 | SIRT2 (0.34) | L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL1543624 | 0.76 | PDXK (0.46) | PLAUMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL856508 | 0.74 | KMT2A (0.37) | PLAUMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5046239 | 0.74 | KMT2A (0.35) | PLAUMEN1KMT2AMAPT | |
| SCHEMBL31430877 | 0.74 | KMT2A (0.37) | PLAUMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1600624 | 0.73 | OPRK1 (0.42) | PLAUMAPK1ALDH1A1PTGDR2HSD17B10 | |
| SCHEMBL21494415 | 0.72 | PLAU (0.33) | PLAUMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105198881-A | Synthesizing process of 5-bromo-3-methyl-1H-pyrazolo [3, 4-B] pyridine | SHANGHAI TITAN TECHNOLOGY CO LTD | 2015-12-30 | — | — | CN | disclosed |