Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10322905 | 0.92 | TPMT (0.42) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL9787608 | 0.90 | TPMT (0.60) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL31318546 | 0.88 | TPMT (0.61) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL29856159 | 0.88 | LMNA (0.46) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL10323282 | 0.88 | TPMT (0.61) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL10323237 | 0.88 | TPMT (0.61) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL10323392 | 0.87 | HPGD (0.45) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL29856356 | 0.85 | TPMT (0.41) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL10322563 | 0.85 | TPMT (0.41) | TPMTCA1CA2CA12CA4 | |
| SCHEMBL10323062 | 0.85 | TNFRSF1A (0.44) | TPMTCA1CA2CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105315245-A | Benzofuran derivative, preparation method and application thereof | CHINA RESOURCES SAIKE PHARMACEUTICAL CO LTD | 2016-02-10 | — | — | CN | disclosed |