Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28046034 | 0.88 | TPMT (0.49) | TPMTGPR35HPGDALDH1A1CA12 | |
| SCHEMBL3546802 | 0.82 | TPMT (0.79) | TPMTKMT2AHSD17B10TSHRAPOBEC3A | |
| SCHEMBL9787608 | 0.82 | TPMT (0.60) | TPMTHSD17B10HTTGPR35HPGD | |
| SCHEMBL10323282 | 0.81 | TPMT (0.61) | TPMTGPR35HPGDALDH1A1CA12 | |
| SCHEMBL10322905 | 0.81 | TPMT (0.42) | TPMTGPR35HPGDALDH1A1CA12 | |
| SCHEMBL10323237 | 0.81 | TPMT (0.61) | TPMTKMT2AHSD17B10HTTTTR | |
| SCHEMBL29856159 | 0.81 | LMNA (0.46) | TPMTHTTGPR35HPGDALDH1A1 | |
| SCHEMBL10323392 | 0.79 | HPGD (0.45) | TPMTHTTGPR35HPGDALDH1A1 | |
| SCHEMBL10323062 | 0.78 | TNFRSF1A (0.44) | TPMTGPR35HPGDALDH1A1CA12 | |
| SCHEMBL29856356 | 0.78 | TPMT (0.41) | TPMTHSD17B10GPR35HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |