Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856146 | 0.87 | HPGD (0.37) | KDM4EHSD17B10HPGDALDH1A1GPR35 | |
| SCHEMBL29856585 | 0.87 | GAA (0.40) | KDM4EHSD17B10HPGDALDH1A1CA12 | |
| SCHEMBL28046034 | 0.85 | TPMT (0.49) | TPMTHPGDALDH1A1CA12CA1 | |
| SCHEMBL9787608 | 0.80 | TPMT (0.60) | TPMTKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL10323282 | 0.78 | TPMT (0.61) | TPMTHPGDALDH1A1CA12CA1 | |
| SCHEMBL31318546 | 0.78 | TPMT (0.61) | TPMTHSD17B10HPGDALDH1A1CA12 | |
| SCHEMBL29856159 | 0.78 | LMNA (0.46) | TPMTHPGDALDH1A1CA12CA1 | |
| SCHEMBL10322905 | 0.78 | TPMT (0.42) | TPMTHPGDALDH1A1CA12CA1 | |
| SCHEMBL10323237 | 0.78 | TPMT (0.61) | TPMTKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL10323392 | 0.77 | HPGD (0.45) | TPMTHPGDALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169974-A1 | INHIBITORS OF URAT1 AND PHARMACEUTICAL USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |