SCHEMBL28046072

SCHEMBL28046072

NNP(=O)(O)Oc1ccccc1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
HDAC6 Q9UBN7 1/20 0.44
MAPK1 P28482 1/20 0.43
PTK2B Q14289 1/20 0.43
POLB P06746 3/20 0.42
PKM P14618 2/20 0.42
GAA P10253 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
RAB9A P51151 1/20 0.39
SENP2 Q9HC62 1/20 0.37
SENP1 Q9P0U3 1/20 0.37
INPPL1 O15357 1/20 0.36
INPP5B P32019 1/20 0.36
INPP5A Q14642 1/20 0.36
SFN P31947 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2127225 0.79 LMNA (0.64) LMNASMN1; SMN2MAPK1PTK2BPOLB
SCHEMBL2472082 0.79 SMN1; SMN2 (0.64) LMNASMN1; SMN2MAPK1PTK2BPOLB
SCHEMBL30557968 0.79 SMN1; SMN2 (0.64) LMNASMN1; SMN2MAPK1PTK2BPOLB
SCHEMBL28694226 0.78 SMN1; SMN2 (0.58) LMNASMN1; SMN2MAPK1PTK2BPOLB
SCHEMBL28200093 0.77 INPPL1 (0.33) LMNASMN1; SMN2MAPK1INPPL1INPP5A
Hydrochloric Acid SCHEMBL29188656 0.77 LMNA (0.62) LMNASMN1; SMN2MAPK1PTK2BPOLB
SCHEMBL9492467 0.77 SMN1; SMN2 (0.62) LMNASMN1; SMN2HDAC6MAPK1PTK2B
SCHEMBL28856235 0.76 LMNA (0.39) LMNASMN1; SMN2MAPK1PKMGAA
SCHEMBL28853887 0.76 SMN1; SMN2 (0.60) LMNASMN1; SMN2MAPK1PTK2BPOLB
SCHEMBL2035293 0.74 LMNA (0.69) LMNASMN1; SMN2HDAC6MAPK1PTK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105198772-A Method for preparing 2-chlorophenylhydrazine phosphate TIANJIN CHEM REAGENT RES INST 2015-12-30 CN claimed
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed
CN-105198772-A Method for preparing 2-chlorophenylhydrazine phosphate TIANJIN CHEM REAGENT RES INST 2015-12-30 CN disclosed