SCHEMBL28856235

SCHEMBL28856235

NNP(=O)(O)Oc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
ALDH1A1 P00352 3/20 0.35
MAPT P10636 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MAPK1 P28482 1/20 0.35
INPPL1 O15357 3/20 0.34
INPP5A Q14642 2/20 0.34
INPP5B P32019 1/20 0.34
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP3 P08254 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
MMP8 P22894 1/20 0.32
MMP14 P50281 1/20 0.32
CA14 Q9ULX7 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15315299 0.78 INPPL1 (0.58) LMNAALDH1A1MAPTNPSR1MAPK1
SCHEMBL28856233 0.77 ALDH1A1 (0.38) ALDH1A1MAPTINPPL1INPP5AINPP5B
SCHEMBL28046072 0.76 LMNA (0.59) LMNAMAPK1INPPL1INPP5AINPP5B
SCHEMBL28200093 0.75 INPPL1 (0.33) LMNAALDH1A1MAPK1INPPL1INPP5A
SCHEMBL18406961 0.75 LMNA (0.42) LMNAALDH1A1MAPTNPSR1MAPK1
SCHEMBL28200207 0.74 CA1 (0.40) ALDH1A1MAPTKDM4EGAACA14
SCHEMBL22477311 0.72 LMNA (0.47) LMNAALDH1A1MAPTNPSR1MAPK1
SCHEMBL8754761 0.71 MPO (0.36) LMNAALDH1A1MAPTNPSR1MAPK1
SCHEMBL3730480 0.70 MPO (0.38) LMNAALDH1A1MAPTNPSR1MAPK1
SCHEMBL28200081 0.69 ALDH1A1 (0.33) LMNAALDH1A1INPPL1INPP5AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed