Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | APP | P05067 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1121005 | 0.86 | ALOX5 (0.48) | OPRM1OPRD1OPRK1OPRL1ALOX5 | |
| SCHEMBL1120960 | 0.80 | ALOX5 (0.44) | OPRM1OPRD1OPRK1OPRL1ALOX5 | |
| SCHEMBL16979034 | 0.79 | OPRM1 (0.41) | OPRM1OPRD1OPRK1OPRL1ALOX5 | |
| SCHEMBL3576114 | 0.77 | OPRM1 (0.40) | OPRM1OPRD1OPRK1OPRL1ALOX5 | |
| SCHEMBL13876257 | 0.76 | OPRM1 (0.59) | OPRM1OPRD1OPRK1OPRL1ALOX5 | |
| SCHEMBL18253218 | 0.74 | HSD11B1 (0.48) | OPRM1OPRD1OPRK1OPRL1ALOX5 | |
| SCHEMBL5642733 | 0.74 | OPRM1 (0.33) | OPRM1 | |
| SCHEMBL5644519 | 0.74 | OPRM1 (0.39) | OPRM1DRD2DRD4DRD3 | |
| SCHEMBL10316602 | 0.73 | OPRM1 (0.40) | OPRM1OPRD1OPRK1OPRL1ALOX5 | |
| SCHEMBL3583315 | 0.72 | ALDH1A1 (0.47) | OPRM1OPRD1OPRK1OPRL1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458931-A | Antibacterial quinazolin-4 (3H) -one derivatives | 埃科特莱茵药品有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105531264-A | Antibacterial 2H-indazole derivatives | ACTELION PHARMACEUTICALS LTD | 2016-04-27 | — | — | CN | disclosed |