Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK4 | Q13043 | 11/20 | 0.61 |
| ▸ | EGFR | P00533 | 9/20 | 0.60 |
| ▸ | ERBB2 | P04626 | 9/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22419601 | 0.84 | EGFR (0.71) | STK4EGFRERBB2 | |
| SCHEMBL1897571 | 0.83 | EGFR (0.85) | STK4EGFRERBB2 | |
| SCHEMBL20584416 | 0.83 | EGFR (0.71) | STK4EGFRERBB2 | |
| SCHEMBL30132269 | 0.83 | EGFR (0.72) | STK4EGFRERBB2 | |
| SCHEMBL2131741 | 0.83 | EGFR (0.72) | STK4EGFRERBB2 | |
| SCHEMBL29670932 | 0.83 | EGFR (0.72) | STK4EGFRERBB2 | |
| SCHEMBL27460925 | 0.81 | EGFR (0.77) | STK4EGFRERBB2 | |
| SCHEMBL6381507 | 0.80 | EGFR (0.82) | STK4EGFRERBB2 | |
| SCHEMBL28547991 | 0.79 | EGFR (0.64) | STK4EGFRERBB2 | |
| SCHEMBL28547159 | 0.78 | STK4 (0.70) | STK4EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175331-A | Preparation method for EGFR molecule targeting antitumor drug | JIANGSU SZYY GROUP PHARMACEUTICAL LTD | 2015-12-23 | — | — | CN | disclosed |