Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28497474 | 0.86 | GSR (0.42) | LMNAKDM4EADRA2CADRA2AHIF1A | |
| SCHEMBL18193017 | 0.83 | GSR (0.43) | LMNAKMT2AGSRALDH1A1MAPK1 | |
| SCHEMBL8094320 | 0.83 | KMT2A (0.42) | LMNAKDM4EADRA2CADRA2AHIF1A | |
| SCHEMBL6281430 | 0.83 | LMNA (0.46) | LMNAKDM4EKMT2AMAPTNPSR1 | |
| SCHEMBL5690880 | 0.78 | KDM4E (0.45) | LMNAKDM4EADRA2CADRA2AHIF1A | |
| SCHEMBL27916936 | 0.77 | GSR (0.44) | LMNAADRA2CKMT2AGSRALDH1A1 | |
| SCHEMBL1828130 | 0.77 | ALDH1A1 (0.41) | LMNAKDM4EKMT2AMAPTNPSR1 | |
| Nitric Acid SCHEMBL9875242 | 0.76 | LMNA (0.41) | LMNAKDM4EADRA2CADRA2AHIF1A | |
| SCHEMBL1357640 | 0.76 | KDM4E (0.50) | LMNAKDM4EADRA2CADRA2AHIF1A | |
| SCHEMBL8670434 | 0.76 | KDM4E (0.50) | LMNAKDM4EADRA2CADRA2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103864637-B | A kind of N-(β-4-nitro alkyl) preparation method of amides | XIHUA UNIVERSITY (CN) | 2015-12-02 | — | — | CN | disclosed |