Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1357640 | 1.00 | KDM4E (0.50) | KDM4EADRA2CLMNAADRA2AHIF1A | |
| SCHEMBL8432973 | 1.00 | KDM4E (0.50) | KDM4EADRA2CLMNAADRA2AHIF1A | |
| SCHEMBL8431549 | 1.00 | KDM4E (0.50) | KDM4EADRA2CLMNAADRA2AHIF1A | |
| SCHEMBL11798974 | 0.84 | TYR (0.42) | KDM4ELMNAHIF1AALDH1A1KMT2A | |
| SCHEMBL11795819 | 0.82 | ACHE (0.42) | KDM4ELMNAALDH1A1KMT2AMAPT | |
| SCHEMBL18116758 | 0.81 | ALDH1A1 (0.53) | KDM4ELMNAALDH1A1KMT2AMAPT | |
| SCHEMBL27339647 | 0.81 | ADRB2 (0.41) | ALDH1A1MAPTSLC6A4CYP2D6ALOX15 | |
| SCHEMBL4703227 | 0.81 | ALDH1A1 (0.40) | KDM4EALDH1A1KMT2AMAPTNPSR1 | |
| SCHEMBL29478063 | 0.80 | ADRB1 (0.57) | KDM4EADRA2CLMNAADRA2AHIF1A | |
| SCHEMBL30352856 | 0.80 | ADRB1 (0.57) | KDM4EADRA2CLMNAADRA2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750802-A | (1R*, 2S)-1-phenyl-2-nitroalcohols and method for producing same | AMVAC CHEMICAL CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |