Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.34 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 4/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | WRN | Q14191 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28185681 | 0.90 | HCAR2 (0.34) | CA1CA2GPR35HCAR2TTR | |
| SCHEMBL27775494 | 0.84 | RARB (0.31) | RARBRARGRXRA | |
| SCHEMBL27770636 | 0.82 | NAPRT (0.39) | DHODH | |
| SCHEMBL27558474 | 0.80 | HCAR3 (0.33) | HCAR2TTRHCAR3 | |
| SCHEMBL28123303 | 0.79 | RXRA (0.33) | RARBRXRA | |
| SCHEMBL28853255 | 0.79 | TSHR (0.36) | DHODH | |
| SCHEMBL27899605 | 0.79 | FOLH1 (0.31) | — | |
| SCHEMBL27371651 | 0.78 | BCL2L1 (0.38) | GPR35HCAR2HCAR3RARBRARG | |
| SCHEMBL28056804 | 0.76 | CA1 (0.39) | CA1CA2GPR35HCAR2KDM4E | |
| SCHEMBL27459534 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107854434-A | Include poly- (ε caprolactones) and polyoxyethylated pharmaceutical dosage form | 普渡制药公司 | 2018-03-30 | — | — | CN | disclosed |
| CN-105294653-B | The preparation technology of Vonoprazan fumarate | 山东罗欣药业集团股份有限公司 | 2017-08-15 | — | — | CN | disclosed |
| CN-105294653-A | Preparation technology for vonoprazan fumarate | SHANDONG LUOXIN PHARMACEUTICAL GROUP CO LTD | 2016-02-03 | — | — | CN | disclosed |