Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28185681 | 0.80 | HCAR2 (0.34) | HCAR3HCAR2TTR | |
| SCHEMBL28046652 | 0.80 | CA1 (0.36) | HCAR3HCAR2TTR | |
| SCHEMBL27775494 | 0.80 | RARB (0.31) | — | |
| SCHEMBL28056804 | 0.75 | CA1 (0.39) | HCAR2 | |
| SCHEMBL27775508 | 0.75 | HCAR3 (0.36) | HCAR3HCAR2 | |
| SCHEMBL27371651 | 0.74 | BCL2L1 (0.38) | HCAR3HCAR2 | |
| SCHEMBL19344710 | 0.71 | — | — | |
| SCHEMBL27459534 | 0.71 | — | — | |
| SCHEMBL28857964 | 0.70 | ALDH1A1 (0.40) | HCAR2 | |
| SCHEMBL28853255 | 0.70 | TSHR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102781942-A | Disubstituted octahy-dropyrrolo [3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV | 2012-11-14 | — | — | CN | disclosed |
| CN-1328247-C | N-biphenylmethyl aminocycloalkanecarboxamide derivatives with a substiituent on the methyl useful as bradykinin antagonists | MERCK & CO INC (US) | 2007-07-25 | — | — | CN | disclosed |
| CN-1630633-A | N-biphenylmethylaminocycloalkane carboxamide derivatives with substituents on the methyl group thereof as bradykinin antagonists | MERCK & CO INC (US) | 2005-06-22 | — | — | CN | disclosed |