Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.39 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729683 | 0.80 | SYK (0.43) | KMT2AL3MBTL1CA12CA1CA7 | |
| SCHEMBL27863550 | 0.75 | KMT2A (0.44) | KMT2AL3MBTL1AKT1CA12CA1 | |
| SCHEMBL6865331 | 0.70 | KMT2A (0.60) | KMT2AL3MBTL1SCN9A | |
| SCHEMBL5425216 | 0.70 | KMT2A (0.60) | KMT2AL3MBTL1SCN9A | |
| SCHEMBL28307326 | 0.69 | CRHBP (0.44) | KMT2AL3MBTL1AKT1HDAC1HDAC6 | |
| SCHEMBL27551968 | 0.69 | ALDH1A1 (0.46) | KMT2AL3MBTL1 | |
| SCHEMBL1815532 | 0.69 | KMT2A (0.65) | KMT2AL3MBTL1NPFFR1NPFFR2SIGMAR1 | |
| SCHEMBL7981883 | 0.68 | NPFFR1 (0.53) | KMT2AL3MBTL1AKT1NPFFR1NPFFR2 | |
| SCHEMBL7972083 | 0.68 | SIGMAR1 (0.57) | AKT1CA12CA1CA7CA14 | |
| SCHEMBL8919552 | 0.68 | KMT2A (0.57) | KMT2AL3MBTL1CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111155-A | Synthesis method of tert-butyl 4,7-diazaspiro[2.5]octyl-7-formate | WUHAN INST TECHNOLOGY | 2015-12-02 | — | — | CN | disclosed |