Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28463477 | 0.83 | GAA (0.48) | GAACYP2C19ALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL15483137 | 0.78 | LMNA (0.41) | GAAALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL13653517 | 0.76 | GAA (0.51) | GAAALDH1A1L3MBTL1HSD17B10TSHR | |
| SCHEMBL4817806 | 0.76 | HPGD (0.53) | ALDH1A1L3MBTL1HSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL12497355 | 0.76 | KDM4E (0.47) | GAACYP2C19ALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL11675635 | 0.72 | HSD17B10 (0.43) | ALDH1A1L3MBTL1HSD17B10KMT2AKDM4E | |
| SCHEMBL16766556 | 0.72 | PTK2 (0.38) | GAACYP2C19TSHRKMT2AKDM4E | |
| SCHEMBL28183310 | 0.71 | L3MBTL1 (0.51) | GAACYP2C19ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL10952765 | 0.71 | NPSR1 (0.53) | GAAALDH1A1HSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL27831985 | 0.71 | MAPK3 (0.48) | GAACYP2C19ALDH1A1HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105120860-A | Histone deacetylase inhibitors | BIOMARIN PHARM INC | 2015-12-02 | — | — | CN | disclosed |