Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | QPCT | Q16769 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ADH5 | P11766 | 2/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL17317416 | 0.93 | NFKB1 (0.58) | NFKB1QPCTHSD17B10QPCTLNAPRT | |
| Benzil SCHEMBL27641833 | 0.89 | NFKB1 (0.54) | NFKB1QPCTHSD17B10QPCTLTBXAS1 | |
| Niacin SCHEMBL28562274 | 0.87 | ALDH1A1 (0.66) | NFKB1QPCTHSD17B10QPCTLTSHR | |
| Phthalic Acid SCHEMBL12076342 | 0.86 | NFKB1 (0.54) | NFKB1QPCTHSD17B10QPCTLTBXAS1 | |
| 1-Methylimidazole SCHEMBL28947361 | 0.80 | NFKB1 (0.75) | NFKB1QPCTHSD17B10QPCTLTBXAS1 | |
| 1-Methylimidazole SCHEMBL19356956 | 0.80 | NFKB1 (0.75) | NFKB1QPCTHSD17B10QPCTLTBXAS1 | |
| Salicylic Acid SCHEMBL28225946 | 0.80 | ALDH1A1 (0.56) | NFKB1QPCTHSD17B10QPCTLNAPRT | |
| Phenol SCHEMBL11630320 | 0.79 | QPCT (0.60) | NFKB1QPCTHSD17B10QPCTLTSHR | |
| Benzoic Acid SCHEMBL2518951 | 0.79 | TBXAS1 (0.59) | TBXAS1MEN1LMNAKMT2ACYP19A1 | |
| 1-Methylimidazole SCHEMBL11341886 | 0.78 | NFKB1 (0.71) | NFKB1QPCTHSD17B10QPCTLTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116448893-A | Characterization method of cellulose molecular weight | 中国科学院化学研究所 | 2023-07-18 | — | — | CN | claimed |
| WO-2022048910-A1 | STIMULATING / SENSING ELECTRODE COMPRISING A PRINTABLE ADHESIVE | HENKEL AG & CO. KGAA (DE) | 2022-03-10 | — | — | WO | claimed |
| US-20100239673-A1 | Blood compatible nanomaterials and methods of making and using the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-09-23 | — | — | US | claimed |
| WO-2008045021-A2 | BLOOD COMPATIBLE NANOMATERIALS AND METHODS OF MAKING AND USING THE SAME | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2008-04-17 | — | — | WO | claimed |
| US-6946298-B2 | Karl fischer reagent | SIGMA-ALDRICH CO. (US) | 2005-09-20 | — | — | US | claimed |
| US-20020127726-A1 | Karl fischer reagent | SIGMA-ALDRICH CO. | 2002-09-12 | — | — | US | claimed |
| CN-116448893-A | Characterization method of cellulose molecular weight | 中国科学院化学研究所 | 2023-07-18 | — | — | CN | disclosed |
| CN-116448893-A | Characterization method of cellulose molecular weight | 中国科学院化学研究所 | 2023-07-18 | — | — | CN | disclosed |
| US-20100239673-A1 | Blood compatible nanomaterials and methods of making and using the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-09-23 | — | — | US | disclosed |
| CN-101041637-B | Chiral amine protonic acid salt containing imidazole sulfur ether structure and preparation method and usage thereof | UNIV ZHEJIANG TECHNOLOGY | 2010-06-09 | — | — | CN | disclosed |
| WO-2008045021-A2 | BLOOD COMPATIBLE NANOMATERIALS AND METHODS OF MAKING AND USING THE SAME | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2008-04-17 | — | — | WO | disclosed |
| CN-101041637-A | Chirality amine protonic acid salt containing imidazole sulfur ether structure and preparation method and usage thereof | UNIV ZHEJIANG TECHNOLOGY (CN) | 2007-09-26 | — | — | CN | disclosed |
| US-6946298-B2 | Karl fischer reagent | SIGMA-ALDRICH CO. (US) | 2005-09-20 | — | — | US | disclosed |
| US-20020127726-A1 | Karl fischer reagent | SIGMA-ALDRICH CO. | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100239673-A1 | Blood compatible nanomaterials and methods of making and using the same | MB, ICAM1, F3 | NFKB1 4010/4885QPCT 3319/4885HSD17B10 3701/4885 |
| US-20020127726-A1 | Karl fischer reagent | MASTL, KARS1, DOT1L | NFKB1 1824/4885QPCT 4238/4885HSD17B10 4115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.