Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3GNRHRMPLPDE3APDE3BPDE4APDE4BPDE4CPDE4DPPARASLC5A2
The experimentally established mechanism targets of Trifluoromethanesulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.52 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GRK2 | P25098 | 1/20 | 0.30 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.30 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL29160398 | 0.98 | CYP3A4 (0.56) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL28499286 | 0.88 | CYP3A4 (0.50) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Trifluoromethanesulfonic Acid SCHEMBL3008777 | 0.86 | L3MBTL1 (0.40) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Trifluoromethanesulfonamide SCHEMBL28047636 | 0.84 | LMNA (0.50) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Trifluoromethanesulfonic Acid SCHEMBL3785097 | 0.84 | MEN1 (0.50) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Trifluoromethanesulfonamide SCHEMBL28047774 | 0.84 | LMNA (0.50) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL393397 | 0.83 | MEN1 (0.67) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL27857086 | 0.82 | MEN1 (0.43) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL28501392 | 0.82 | CYP3A4 (0.48) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL933567 | 0.81 | MEN1 (0.46) | MEN1LMNAKMT2ACYP3A4SLC5A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503540-A | Method for preparation of benzene ring phenol compound from alkali lignin | DALIAN INST CHEMICAL PHYSICS CAS | 2016-04-20 | — | — | CN | claimed |
| CN-105315164-A | Environment-friendly choline ionic liquid and preparation method therefor | DALIAN CHEMICAL PHYSICS INST | 2016-02-10 | — | — | CN | claimed |
| CN-114390909-B | Manufacturing technology of skin compatible electrode | 荷兰应用自然科学研究组织TNO | 2024-09-20 | — | — | CN | disclosed |
| CN-117941116-A | Ionic binders for solid state electrodes | 迪金大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-115989294-A | Dry stimulating electrode | 汉高股份有限及两合公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-105503540-A | Method for preparation of benzene ring phenol compound from alkali lignin | DALIAN INST CHEMICAL PHYSICS CAS | 2016-04-20 | — | — | CN | disclosed |
| CN-105315164-A | Environment-friendly choline ionic liquid and preparation method therefor | DALIAN CHEMICAL PHYSICS INST | 2016-02-10 | — | — | CN | disclosed |
| CN-105315164-A | Environment-friendly choline ionic liquid and preparation method therefor | DALIAN CHEMICAL PHYSICS INST | 2016-02-10 | — | — | CN | disclosed |